COMPARISON of 12-hour Fasting and 2-hour Post Prandial Sample Collection and Processing of Lipid Profile among Selected Dyslipidemic Patients from Cagayan de Oro, PHILIPPINES

Abstract

Lipid profile testing continues to be the method of choice for monitoring and predicting cardiovascular risk. Patient adherence to complete 12-hour fasting poses threat to test results validity as it contributes to reduced patient compliance to fasting, and inconvenience from patients with dyslipidemias. The aim of this study is to compare the lipid profile from a 12-hour fasting and 2-hour postprandial over a two-week interval for four weeks. The study followed a descriptive comparative design. Eighty four dyslipidemic subjects were recruited and serum samples were processed. Statistical difference and statistical interaction effects between the analyte measurements across time and patient preparation type was determined. The findings showed that there were no statistical differences between the pairwise comparison of lipid profile measurements between 12-hours fasting and 2-hours postprandial preparation. However, further analysis found a significant interaction between the triglycerides measurements in various time intervals and patient preparation type which indicates that 2-hours postprandial preparation may result in inconsistent triglyceride measurement compared to 12-hour fasting preparation.