Impact of Patient Counseling on Medication Adherence of Hypertensive Patients: A Systematic Review
Keywords:
Systematic review, Hypertension, Patient counseling, Medication adherence, Hypertensive patientAbstract
Background: Poor medication adherence is prevalent in hypertensive patients suffering from chronic diseases. Furthermore, hypertensive patients require lifelong treatment with antihypertensive medication to prevent the development of complications such as cardiovascular diseases.
Objective: The study aimed to assess the level of compliance with medication, the effectiveness of a technology-based intervention in improving medication adherence, and the understanding of hypertension and medication adherence among the selected patients.
Methods: This study conducted a systematic review of the impact of patient counseling and pharmacist intervention on improving medication adherence in patients with hypertension, based on information published from 2000 to 2021, which included 200 research articles. This study reviewed 26 studies that assessed the level of compliance/adherence to medication, the involvement of technology-based interventions to improve medication adherence, and the understanding of hypertension and its relationship to medication adherence, all based on strict inclusion criteria.
Results: The findings of the review pointed out that the presence of patient counseling significantly impacts medication adherence. Several factors influence medication adherence. However, it is expected that patients suffering from chronic conditions such as hypertension have a lower level of medication adherence.
Conclusion: The importance of finding an intervention to promote good medication adherence practices in patients becomes increasingly essential.
References
Abegaz T.M., Shehab A., Gebreyohannes E.A., Bhagavathula A.S., Elnour A.A. Nonadherence to antihypertensive drugs: a systematic review and meta-analysis. Medicine. 2017;96:e5641. doi: 10.1097/MD.0000000000005641.
Abubakar, A., & Sinclair, J. (2020). The Emerging Role of Community Pharmacists in Remote Patient Monitoring Services. Pharmacy (Basel, Switzerland), 8(3), 166. https://doi.org/10.3390/pharmacy8030166
AlShayban, D. M., Naqvi, A. A., Islam, M. A., Almaskeen, M., Almulla, A., Alali, M., AlQaroos, A., Raafat, M., Iqbal, M. S., & Haseeb, A. (2020). Patient Satisfaction and Their Willingness to Pay for a Pharmacist Counseling Session in Hospital and Community Pharmacies in Saudi Healthcare Settings. Frontiers in pharmacology, 11, 138. https://doi.org/10.3389/fphar.2020.00138
Bell, S. P., Schnipper, J. L., Goggins, K., Bian, A., Shintani, A., Roumie, C. L., Dalal, A. K., Jacobson, T. A., Rask, K. J., Vaccarino, V., Gandhi, T. K., Labonville, S. A., Johnson, D., Neal, E. B., Kripalani, S., & Pharmacist Intervention for Low Literacy in Cardiovascular Disease (PILL-CVD) Study Group (2016). Effect of Pharmacist Counseling Intervention on Health Care Utilization Following Hospital Discharge: A Randomized Controlled Trial. Journal of general internal medicine, 31(5), 470–477. https://doi.org/10.1007/s11606-016-3596-3
Booth, A. Searching for qualitative research for inclusion in systematic reviews: a structured methodological review. Syst Rev 5, 74 (2016). https://doi.org/10.1186/s13643-016-0249-x
Burnier, M., Polychronopoulou, E., & Wuerzner, G. (2020). Hypertension and Drug Adherence in the Elderly. Frontiers in cardiovascular medicine, 7, 49. https://doi.org/10.3389/fcvm.2020.00049
Cho, M. H., Shin, D. W., Chang, S. A., Lee, J. E., Jeong, S. M., Kim, S. H., Yun, J. M., & Son, K. (2018). Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia. Scientific reports, 8(1), 11688. https://doi.org/10.1038/s41598-018-29974-7
Cutler, D. M., & Everett, W. (2010). Thinking outside the pillbox--medication adherence as a priority for health care reform. The New England journal of medicine, 362(17), 1553–1555. https://doi.org/10.1056/NEJMp1002305
Elbur, A. I. (2015). LEVEL OF ADHERENCE TO LIFESTYLE CHANGES AND MEDICATIONS AMONG MALE HYPERTENSIVE PATIENTS IN TWO HOSPITALS IN TAIF; KINGDOM OF SAUDI ARABIA. International Journal of Pharmacy and Pharmaceutical Sciences, 7(4), 168–172. Retrieved from https://journals.innovareacademics.in/index.php/ijpps/article/view/4804
Friedman, R. H., Kazis, L. E., Jette, A., Smith, M. B., Stollerman, J., Torgerson, J., & Carey, K. (1996). A telecommunications system for monitoring and counseling patients with hypertension. Impact on medication adherence and blood pressure control. American journal of hypertension, 9(4 Pt 1), 285–292. https://doi.org/10.1016/0895-7061(95)00353-3
Gellad, W. F., Grenard, J. L., & Marcum, Z. A. (2011). A systematic review of barriers to medication adherence in the elderly: looking beyond cost and regimen complexity. The American journal of geriatric pharmacotherapy, 9(1), 11–23. https://doi.org/10.1016/j.amjopharm.2011.02.004
Hadi, N., & ROSTAMI, G. N. (2004). Determinant factors of medication compliance in hypertensive patients of Shiraz, Iran. Archives of Iranian Medicine, 7(4), 292-296.
Hyre, A. D., Krousel-Wood, M. A., Muntner, P., Kawasaki, L., & DeSalvo, K. B. (2007). Prevalence and predictors of poor antihypertensive medication adherence in an urban health clinic setting. Journal of clinical hypertension (Greenwich, Conn.), 9(3), 179–186. https://doi.org/10.1111/j.1524-6175.2007.06372.x
Jin, H., Kim, Y., & Rhie, S. J. (2016). Factors Affecting Medication Adherence in Elderly People. Patient preference and adherence, 10, 2117.
Leguelinel-Blache, G., Dubois, F., Bouvet, S., Roux-Marson, C., Arnaud, F., Castelli, C., Ray, V., Kinowski, J. M., & Sotto, A. (2015). Improving Patients' Adherence to Primary Medications: The Value of Pharmaceutical Counseling. Medicine, 94(41), e1805. https://doi.org/10.1097/MD.0000000000001805
MacGill, M. (2019). What is a systematic review in research? Retrieved October 3, 2021, from Medical News Today https://www.medicalnewstoday.com/articles/281283
Mathew, A., Paluri, V., & Venkateswaramurthy, N. (2016). A Study on Impact of Clinical Pharmacist Interventions on Relationship between Treatment Satisfaction and Medication Adherence in Hypertensive Patients. (Pt. 190-197). J. Pharm. Sci., 8(4). https://pharmainfo.in/jpsr/Documents/Volumes/vol8Issue04/jpsr08041603.pdf
Newman-Casey, P. A., Weizer, J. S., Heisler, M., Lee, P. P., & Stein, J. D. (2013). Systematic review of educational interventions to improve glaucoma medication adherence. Seminars in ophthalmology, 28(3), 191–201. https://doi.org/10.3109/08820538.2013.771198
Omboni, S., & Caserini, M. (2018). Effectiveness of pharmacist's intervention in the management of cardiovascular diseases. Open heart, 5(1), e000687. https://doi.org/10.1136/openhrt-2017-000687
Osterberg, L., & Blaschke, T. (2005). Adherence to medication. The New England journal of medicine, 353(5), 487–497. https://doi.org/10.1056/NEJMra050100
Ramli, A., Ahmad, N. S., & Paraidathathu, T. (2012). Medication adherence among hypertensive patients of primary health clinics in Malaysia. Patient preference and adherence, 6, 613–622. https://doi.org/10.2147/PPA.S34704
Sabaté, E., & Sabaté, E. (Eds.). (2003). Adherence to Long-Term Therapies: Evidence for Action. World Health Organization.
Saleem, F., Hassali, M. A., Shafie, A. A., Ul Haq, N., Farooqui, M., Aljadhay, H., & Ahmad, F. U. (2015). Pharmacist intervention in improving hypertension-related knowledge, treatment medication adherence and health-related quality of life: a non-clinical randomized controlled trial. Health expectations : an international journal of public participation in health care and health policy, 18(5), 1270–1281. https://doi.org/10.1111/hex.12101
Sanii, Y., Torkamandi, H., Gholami, K., Hadavand, N., & Javadi, M. (2016). Role of pharmacist counseling in pharmacotherapy quality improvement. Journal of research in pharmacy practice, 5(2), 132–137. https://doi.org/10.4103/2279-042X.179580
Simpson R. J., Jr (2006). Challenges for improving medication adherence. JAMA, 296(21), 2614–2616. https://doi.org/10.1001/jama.296.21.jed60074
Spence, M. M., Makarem, A. F., Reyes, S. L., Rosa, L. L., Nguyen, C., Oyekan, E. A., & Kiyohara, A. T. (2014). Evaluation of an outpatient pharmacy clinical services program on adherence and clinical outcomes among patients with diabetes and/or coronary artery disease. Journal of managed care & specialty pharmacy, 20(10), 1036–1045. https://doi.org/10.18553/jmcp.2014.20.10.1036
Taitel, M., Jiang, J., Rudkin, K., Ewing, S., & Duncan, I. (2012). The impact of pharmacist face-to-face counseling to improve medication adherence among patients initiating statin therapy. Patient preference and adherence, 6, 323–329. https://doi.org/10.2147/PPA.S29353
Thomas, J. A., Snigdha, K. S., Karanath, P. M., & Swaroop, A. M. (2017). Impact of patient counseling on knowledge, attitude, and practice of hypertensive patients in a tertiary care hospital. Int. J. Pharm. Pharm. Sci., 9(9), 122–129.
Unni, E. J., Olson, J. L., & Farris, K. B. (2014). Revision and validation of the medication adherence reasons scale (MAR-scale). Current medical research and opinion, 30(2), 211–221.
Vrijens, B., Tousset, E., Rode, R., Bertz, R., Mayer, S., & Urquhart, J. (2005). Successful projection of the time course of drug concentration in plasma during a 1-year period from electronically compiled dosing-time data used as input to individually parameterized pharmacokinetic models. Journal of clinical pharmacology, 45(4), 461–467. https://doi.org/10.1177/0091270004274433
Zanni, G.R., PhD. (2021). Counseling for Improved Medication Adherence. Retrieved October 4, 2021, from Pharmacy Times, https://www.pharmacytimes.com/view/counseling-for-improved-medication-adherence
Zerafa, N., Zarb Adami, M., & Galea, J. (2011). Impact of drugs counselling by an undergraduate pharmacist on cardiac surgical patient's compliance to medicines. Pharmacy practice, 9(3), 156–161.
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